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rs42041 |
SNP |
PedAM |
snpId=rs42041; pubmedId=19435719; geneId=1021; geneSymbol=CDK6; diseaseId=umls:C0003873; sourceId=BeFree; sentence=However, there was no evidence for association of rs42041 (CDK6) and rs6682654 (CD244) with RA susceptibility in this UK population.; score=0.255287959; Year=2010; geneSymbol_dbSNP=CDK6; CHROMOSOME=7; POS=92617430; REF=C; ALT=G |
details
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rs42041 |
SNP |
PedAM |
snpId=rs42041; pubmedId=19644859; geneId=1021; geneSymbol=CDK6; diseaseId=umls:C0003873; sourceId=BeFree; sentence=The TT and CC/CG genotypes of 2 single-nucleotide polymorphisms, rs4810485 (CD40) and rs42041 (CDK6), respectively, were associated with a higher rate of joint destruction in ACPA-positive RA patients (P=0.003 and P=0.012, respectively), with rs4810485 being significant after Bonferroni correction for multiple testing.; score=0.255287959; Year=2009; geneSymbol_dbSNP=CDK6; CHROMOSOME=7; POS=92617430; REF=C; ALT=G |
details
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rs42041 |
SNP |
PedAM |
snpId=rs42041; pubmedId=18794853; geneId=1021; geneSymbol=CDK6; diseaseId=umls:C0003873; sourceId=GAD; sentence=[Common variants at CD40 and other loci confer risk of rheumatoid arthritis.]; score=0.255287959; Year=2008; geneSymbol_dbSNP=CDK6; CHROMOSOME=7; POS=92617430; REF=C; ALT=G |
details
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rs42041 |
SNP |
PedAM |
snpId=rs42041; pubmedId=19435719; geneId=51744; geneSymbol=CD244; diseaseId=umls:C0003873; sourceId=BeFree; sentence=However, there was no evidence for association of rs42041 (CDK6) and rs6682654 (CD244) with RA susceptibility in this UK population.; score=0.248544182; Year=2010; geneSymbol_dbSNP=CDK6; CHROMOSOME=7; POS=92617430; REF=C; ALT=G |
details
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rs4239702 |
SNP |
PedAM |
snpId=rs4239702; pubmedId=24390342; geneId=958; geneSymbol=CD40; diseaseId=umls:C0003873; sourceId=GWASCAT; sentence=Genetics of rheumatoid arthritis contributes to biology and drug discovery.; score=0.277186332; Year=2013; geneSymbol_dbSNP=CD40; CHROMOSOME=20; POS=46120612; REF=T; ALT=C |
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rs4272 |
SNP |
PedAM |
snpId=rs4272; pubmedId=24390342; geneId=1021; geneSymbol=CDK6; diseaseId=umls:C0003873; sourceId=GWASCAT; sentence=Genetics of rheumatoid arthritis contributes to biology and drug discovery.; score=0.255287959; Year=2013; geneSymbol_dbSNP=CDK6; CHROMOSOME=7; POS=92607515; REF=A; ALT=G |
details
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rs4329505 |
SNP |
PedAM |
snpId=rs4329505; pubmedId=24978393; geneId=3570; geneSymbol=IL6R; diseaseId=umls:C0003873; sourceId=BeFree; sentence=Interleukin-6-receptor polymorphisms rs12083537, rs2228145, and rs4329505 as predictors of response to tocilizumab in rheumatoid arthritis.; score=0.247719925; Year=2014; geneSymbol_dbSNP=IL6R; CHROMOSOME=1; POS=154459944; REF=T; ALT=C |
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rs4452313 |
SNP |
PedAM |
snpId=rs4452313; pubmedId=24390342; geneId=23228; geneSymbol=PLCL2; diseaseId=umls:C0003873; sourceId=GWASCAT; sentence=Genetics of rheumatoid arthritis contributes to biology and drug discovery.; score=0.122367032; Year=2013; geneSymbol_dbSNP=PLCL2; CHROMOSOME=3; POS=17005540; REF=A; ALT=T |
details
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rs4750316 |
SNP |
PedAM |
snpId=rs4750316; pubmedId=18794853; geneId=5588; geneSymbol=PRKCQ; diseaseId=umls:C0003873; sourceId=GAD; sentence=[Common variants at CD40 and other loci confer risk of rheumatoid arthritis.]; score=0.139750581; Year=2008; geneSymbol_dbSNP=DKFZp667F0711; CHROMOSOME=10; POS=6351298; REF=C; ALT=G |
details
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rs4750316 |
SNP |
PedAM |
snpId=rs4750316; pubmedId=20453842; geneId=399716; geneSymbol=DKFZp667F0711; diseaseId=umls:C0003873; sourceId=GAD; sentence=[Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci.]; score=0.004734064; Year=2010; geneSymbol_dbSNP=DKFZp667F0711; CHROMOSOME=10; POS=6351298; REF=C; ALT=G |
details
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rs4750316 |
SNP |
PedAM |
snpId=rs4750316; pubmedId=18794853; geneId=399716; geneSymbol=DKFZp667F0711; diseaseId=umls:C0003873; sourceId=GAD; sentence=[Common variants at CD40 and other loci confer risk of rheumatoid arthritis.]; score=0.004734064; Year=2008; geneSymbol_dbSNP=DKFZp667F0711; CHROMOSOME=10; POS=6351298; REF=C; ALT=G |
details
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rs4774 |
SNP |
PedAM |
snpId=rs4774; pubmedId=22272574; geneId=49; geneSymbol=ACR; diseaseId=umls:C0003873; sourceId=BeFree; sentence=1302 patients fulfilling the 1987 ACR classification criteria for RA were genotyped for the MHCIITA rs3087456 and rs4774 gene polymorphisms to determine the influence of MHCIITA variants in the development of CV events.; score=0.005700279; Year=2012; geneSymbol_dbSNP=CIITA; CHROMOSOME=16; POS=10906991; REF=G; ALT=C |
details
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rs4774 |
SNP |
PedAM |
snpId=rs4774; pubmedId=19221398; geneId=23274; geneSymbol=CLEC16A; diseaseId=umls:C0003873; sourceId=BeFree; sentence=The effect of the MHC2TA rs3087456G/rs4774C haplotype on RA susceptibility was confirmed, and the haplotype was found to be in negative linkage disequilibrium with the CLEC16A rs2903692A/rs6498169A haplotype.; score=0.00554839; Year=2010; geneSymbol_dbSNP=CIITA; CHROMOSOME=16; POS=10906991; REF=G; ALT=C |
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rs4810485 |
SNP |
PedAM |
snpId=rs4810485; pubmedId=20498205; geneId=6775; geneSymbol=STAT4; diseaseId=umls:C0003873; sourceId=BeFree; sentence=Eight markers (ie, rs1160542 (AFF3), rs1678542 (KIF5A), rs2476601 (PTPN22), rs3087243 (CTLA4), rs4810485 (CD40), rs5029937 (6q23), rs10760130 (TRAF1/C5) and rs7574865 (STAT4)) were significantly associated with RA by meta-analysis.; score=0.316739695; Year=2010; geneSymbol_dbSNP=CD40; CHROMOSOME=20; POS=46119308; REF=T; ALT=G |
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rs4810485 |
SNP |
PedAM |
snpId=rs4810485; pubmedId=20498205; geneId=3899; geneSymbol=AFF3; diseaseId=umls:C0003873; sourceId=BeFree; sentence=Eight markers (ie, rs1160542 (AFF3), rs1678542 (KIF5A), rs2476601 (PTPN22), rs3087243 (CTLA4), rs4810485 (CD40), rs5029937 (6q23), rs10760130 (TRAF1/C5) and rs7574865 (STAT4)) were significantly associated with RA by meta-analysis.; score=0.129001189; Year=2010; geneSymbol_dbSNP=CD40; CHROMOSOME=20; POS=46119308; REF=T; ALT=G |
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rs4810485 |
SNP |
PedAM |
snpId=rs4810485; pubmedId=23678157; geneId=3119; geneSymbol=HLA-DQB1; diseaseId=umls:C0003873; sourceId=BeFree; sentence=Among these associations, we found that 8 single-nucleotide polymorphisms (SNP; rs1600249, rs2736340, rs3093023, rs3093024, rs4810485, rs615672, rs660895, and rs9272219) serve as cis-effect regulators of the corresponding eQTL genes (BLK and CD4 in non-HLA region; CCR6, HLA-DQA1, and HLA-DQB1 in HLA region) that also were differentially expressed in RA-related cell groups.; score=0.051226702; Year=2014; geneSymbol_dbSNP=CD40; CHROMOSOME=20; POS=46119308; REF=T; ALT=G |
details
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rs4810485 |
SNP |
PedAM |
snpId=rs4810485; pubmedId=19644859; geneId=1021; geneSymbol=CDK6; diseaseId=umls:C0003873; sourceId=BeFree; sentence=The TT and CC/CG genotypes of 2 single-nucleotide polymorphisms, rs4810485 (CD40) and rs42041 (CDK6), respectively, were associated with a higher rate of joint destruction in ACPA-positive RA patients (P=0.003 and P=0.012, respectively), with rs4810485 being significant after Bonferroni correction for multiple testing.; score=0.255287959; Year=2009; geneSymbol_dbSNP=CD40; CHROMOSOME=20; POS=46119308; REF=T; ALT=G |
details
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rs4810485 |
SNP |
PedAM |
snpId=rs4810485; pubmedId=20498205; geneId=3798; geneSymbol=KIF5A; diseaseId=umls:C0003873; sourceId=BeFree; sentence=Eight markers (ie, rs1160542 (AFF3), rs1678542 (KIF5A), rs2476601 (PTPN22), rs3087243 (CTLA4), rs4810485 (CD40), rs5029937 (6q23), rs10760130 (TRAF1/C5) and rs7574865 (STAT4)) were significantly associated with RA by meta-analysis.; score=0.254473634; Year=2010; geneSymbol_dbSNP=CD40; CHROMOSOME=20; POS=46119308; REF=T; ALT=G |
details
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rs4810485 |
SNP |
PedAM |
snpId=rs4810485; pubmedId=18794853; geneId=958; geneSymbol=CD40; diseaseId=umls:C0003873; sourceId=GWASCAT; sentence=Common variants at CD40 and other loci confer risk of rheumatoid arthritis.; score=0.277186332; Year=2008; geneSymbol_dbSNP=CD40; CHROMOSOME=20; POS=46119308; REF=T; ALT=G |
details
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rs4810485 |
SNP |
PedAM |
snpId=rs4810485; pubmedId=18794853; geneId=958; geneSymbol=CD40; diseaseId=umls:C0003873; sourceId=GAD; sentence=[Common variants at CD40 and other loci confer risk of rheumatoid arthritis.]; score=0.277186332; Year=2008; geneSymbol_dbSNP=CD40; CHROMOSOME=20; POS=46119308; REF=T; ALT=G |
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