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rs4810485 |
SNP |
PedAM |
snpId=rs4810485; pubmedId=23678157; geneId=3118; geneSymbol=HLA-DQA2; diseaseId=umls:C0003873; sourceId=BeFree; sentence=Among these associations, we found that 8 single-nucleotide polymorphisms (SNP; rs1600249, rs2736340, rs3093023, rs3093024, rs4810485, rs615672, rs660895, and rs9272219) serve as cis-effect regulators of the corresponding eQTL genes (BLK and CD4 in non-HLA region; CCR6, HLA-DQA1, and HLA-DQB1 in HLA region) that also were differentially expressed in RA-related cell groups.; score=0.123452799; Year=2014; geneSymbol_dbSNP=CD40; CHROMOSOME=20; POS=46119308; REF=T; ALT=G |
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rs4810485 |
SNP |
PedAM |
snpId=rs4810485; pubmedId=20453842; geneId=958; geneSymbol=CD40; diseaseId=umls:C0003873; sourceId=GWASCAT; sentence=Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci.; score=0.277186332; Year=2010; geneSymbol_dbSNP=CD40; CHROMOSOME=20; POS=46119308; REF=T; ALT=G |
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rs4810485 |
SNP |
PedAM |
snpId=rs4810485; pubmedId=20498205; geneId=1493; geneSymbol=CTLA4; diseaseId=umls:C0003873; sourceId=BeFree; sentence=Eight markers (ie, rs1160542 (AFF3), rs1678542 (KIF5A), rs2476601 (PTPN22), rs3087243 (CTLA4), rs4810485 (CD40), rs5029937 (6q23), rs10760130 (TRAF1/C5) and rs7574865 (STAT4)) were significantly associated with RA by meta-analysis.; score=0.345272224; Year=2010; geneSymbol_dbSNP=CD40; CHROMOSOME=20; POS=46119308; REF=T; ALT=G |
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rs4810485 |
SNP |
PedAM |
snpId=rs4810485; pubmedId=20498205; geneId=7185; geneSymbol=TRAF1; diseaseId=umls:C0003873; sourceId=BeFree; sentence=Eight markers (ie, rs1160542 (AFF3), rs1678542 (KIF5A), rs2476601 (PTPN22), rs3087243 (CTLA4), rs4810485 (CD40), rs5029937 (6q23), rs10760130 (TRAF1/C5) and rs7574865 (STAT4)) were significantly associated with RA by meta-analysis.; score=0.311201237; Year=2010; geneSymbol_dbSNP=CD40; CHROMOSOME=20; POS=46119308; REF=T; ALT=G |
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rs4810485 |
SNP |
PedAM |
snpId=rs4810485; pubmedId=20498205; geneId=26191; geneSymbol=PTPN22; diseaseId=umls:C0003873; sourceId=BeFree; sentence=Eight markers (ie, rs1160542 (AFF3), rs1678542 (KIF5A), rs2476601 (PTPN22), rs3087243 (CTLA4), rs4810485 (CD40), rs5029937 (6q23), rs10760130 (TRAF1/C5) and rs7574865 (STAT4)) were significantly associated with RA by meta-analysis.; score=0.524345611; Year=2010; geneSymbol_dbSNP=CD40; CHROMOSOME=20; POS=46119308; REF=T; ALT=G |
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rs4810485 |
SNP |
PedAM |
snpId=rs4810485; pubmedId=20498205; geneId=958; geneSymbol=CD40; diseaseId=umls:C0003873; sourceId=BeFree; sentence=Eight markers (ie, rs1160542 (AFF3), rs1678542 (KIF5A), rs2476601 (PTPN22), rs3087243 (CTLA4), rs4810485 (CD40), rs5029937 (6q23), rs10760130 (TRAF1/C5) and rs7574865 (STAT4)) were significantly associated with RA by meta-analysis.; score=0.277186332; Year=2010; geneSymbol_dbSNP=CD40; CHROMOSOME=20; POS=46119308; REF=T; ALT=G |
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rs4810485 |
SNP |
PedAM |
snpId=rs4810485; pubmedId=23166616; geneId=49; geneSymbol=ACR; diseaseId=umls:C0003873; sourceId=BeFree; sentence=One thousand five hundred and seventy-five patients fulfilling the 1987 ACR classification criteria for RA and 1600 matched controls were genotyped for the CD40 rs1883832, rs4810485 and rs1535045 and CD154 rs3092952 and rs3092920 gene polymorphisms, using predesigned TaqMan single nucleotide polymorphism genotyping assays.; score=0.005700279; Year=2012; geneSymbol_dbSNP=CD40; CHROMOSOME=20; POS=46119308; REF=T; ALT=G |
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rs4810485 |
SNP |
PedAM |
snpId=rs4810485; pubmedId=23678157; geneId=640; geneSymbol=BLK; diseaseId=umls:C0003873; sourceId=BeFree; sentence=Among these associations, we found that 8 single-nucleotide polymorphisms (SNP; rs1600249, rs2736340, rs3093023, rs3093024, rs4810485, rs615672, rs660895, and rs9272219) serve as cis-effect regulators of the corresponding eQTL genes (BLK and CD4 in non-HLA region; CCR6, HLA-DQA1, and HLA-DQB1 in HLA region) that also were differentially expressed in RA-related cell groups.; score=0.128458305; Year=2014; geneSymbol_dbSNP=CD40; CHROMOSOME=20; POS=46119308; REF=T; ALT=G |
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rs4937362 |
SNP |
PedAM |
snpId=rs4937362; pubmedId=22446963; geneId=2113; geneSymbol=ETS1; diseaseId=umls:C0003873; sourceId=GAD; sentence=[Meta-analysis identifies nine new loci associated with rheumatoid arthritis in the Japanese population.]; score=0.003181358; Year=2012; geneSymbol_dbSNP=LOC105369568; CHROMOSOME=11; POS=128622844; REF=T; ALT=C |
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rs4942242 |
SNP |
PedAM |
snpId=rs4942242; pubmedId=22491018; geneId=55068; geneSymbol=ENOX1; diseaseId=umls:C0003873; sourceId=GAD; sentence=[Genome-wide association analysis implicates the involvement of eight loci with response to tocilizumab for the treatment of rheumatoid arthritis.]; score=0.002367032; Year=2013; geneSymbol_dbSNP=ENOX1; CHROMOSOME=13; POS=43642928; REF=T; ALT=C |
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rs4944076 |
SNP |
PedAM |
snpId=rs4944076; pubmedId=23636220; geneId=55191; geneSymbol=NADSYN1; diseaseId=umls:C0003873; sourceId=BeFree; sentence=SNPs in the DHCR7/NADSYN1 locus showed evidence of positive association with RA, rs4944076 (P=0.008, odds ratio (OR) 1.14, 95% confidence interval (CI) 1.03-1.24).; score=0.000271442; Year=2013; geneSymbol_dbSNP=NADSYN1; CHROMOSOME=11; POS=71500608; REF=G; ALT=A |
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rs4944076 |
SNP |
PedAM |
snpId=rs4944076; pubmedId=23636220; geneId=128367; geneSymbol=OR10X1; diseaseId=umls:C0003873; sourceId=BeFree; sentence=SNPs in the DHCR7/NADSYN1 locus showed evidence of positive association with RA, rs4944076 (P=0.008, odds ratio (OR) 1.14, 95% confidence interval (CI) 1.03-1.24).; score=0.000271442; Year=2013; geneSymbol_dbSNP=NADSYN1; CHROMOSOME=11; POS=71500608; REF=G; ALT=A |
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rs4963128 |
SNP |
PedAM |
snpId=rs4963128; pubmedId=19714582; geneId=54899; geneSymbol=PXK; diseaseId=umls:C0003873; sourceId=BeFree; sentence=A characteristic single-nucleotide polymorphism (SNP) in each of 9 genetic factors, ITGAM (rs1143679), C8orf13-BLK (rs13277113), TYK2 (rs2304256), 1q25.1 (rs10798269), PXK (rs6445975), KIAA1542 (rs4963128), MECP2 (rs17435), BANK1 (rs17266594), and LY9 (rs509749), was studied in 1,635 patients with RA and 1,906 control subjects from Spain.; score=0.125005506; Year=2009; geneSymbol_dbSNP=PHRF1; CHROMOSOME=11; POS=589564; REF=T; ALT=C |
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rs4963128 |
SNP |
PedAM |
snpId=rs4963128; pubmedId=19714582; geneId=4204; geneSymbol=MECP2; diseaseId=umls:C0003873; sourceId=BeFree; sentence=A characteristic single-nucleotide polymorphism (SNP) in each of 9 genetic factors, ITGAM (rs1143679), C8orf13-BLK (rs13277113), TYK2 (rs2304256), 1q25.1 (rs10798269), PXK (rs6445975), KIAA1542 (rs4963128), MECP2 (rs17435), BANK1 (rs17266594), and LY9 (rs509749), was studied in 1,635 patients with RA and 1,906 control subjects from Spain.; score=0.120814326; Year=2009; geneSymbol_dbSNP=PHRF1; CHROMOSOME=11; POS=589564; REF=T; ALT=C |
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rs4963128 |
SNP |
PedAM |
snpId=rs4963128; pubmedId=19714582; geneId=3684; geneSymbol=ITGAM; diseaseId=umls:C0003873; sourceId=BeFree; sentence=A characteristic single-nucleotide polymorphism (SNP) in each of 9 genetic factors, ITGAM (rs1143679), C8orf13-BLK (rs13277113), TYK2 (rs2304256), 1q25.1 (rs10798269), PXK (rs6445975), KIAA1542 (rs4963128), MECP2 (rs17435), BANK1 (rs17266594), and LY9 (rs509749), was studied in 1,635 patients with RA and 1,906 control subjects from Spain.; score=0.000814326; Year=2009; geneSymbol_dbSNP=PHRF1; CHROMOSOME=11; POS=589564; REF=T; ALT=C |
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rs4963128 |
SNP |
PedAM |
snpId=rs4963128; pubmedId=19714582; geneId=55024; geneSymbol=BANK1; diseaseId=umls:C0003873; sourceId=BeFree; sentence=A characteristic single-nucleotide polymorphism (SNP) in each of 9 genetic factors, ITGAM (rs1143679), C8orf13-BLK (rs13277113), TYK2 (rs2304256), 1q25.1 (rs10798269), PXK (rs6445975), KIAA1542 (rs4963128), MECP2 (rs17435), BANK1 (rs17266594), and LY9 (rs509749), was studied in 1,635 patients with RA and 1,906 control subjects from Spain.; score=0.003181358; Year=2009; geneSymbol_dbSNP=PHRF1; CHROMOSOME=11; POS=589564; REF=T; ALT=C |
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rs4986790 |
SNP |
PedAM |
snpId=rs4986790; pubmedId=18381796; geneId=7099; geneSymbol=TLR4; diseaseId=umls:C0003873; sourceId=BeFree; sentence=The functional variant (Asp299gly) of toll-like receptor 4 (TLR4) influences TLR4-mediated cytokine production in rheumatoid arthritis.; score=0.027141644; Year=2008; geneSymbol_dbSNP=TLR4; CHROMOSOME=9; POS=117713024; REF=A; ALT=G |
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rs4986790 |
SNP |
PedAM |
snpId=rs4986790; pubmedId=25499175; geneId=7099; geneSymbol=TLR4; diseaseId=umls:C0003873; sourceId=BeFree; sentence=Our overall analyses indicated that TLR4 Asp299Gly polymorphism might contribute to RA pathogenesis.; score=0.027141644; Year=2014; geneSymbol_dbSNP=TLR4; CHROMOSOME=9; POS=117713024; REF=A; ALT=G |
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rs4986790 |
SNP |
PedAM |
snpId=rs4986790; pubmedId=18180278; geneId=114609; geneSymbol=TIRAP; diseaseId=umls:C0003873; sourceId=BeFree; sentence=The Mal S180L and TLR4 G299D polymorphisms do not contribute to RA susceptibility or severity either individually or in combination.; score=0.000542884; Year=2008; geneSymbol_dbSNP=TLR4; CHROMOSOME=9; POS=117713024; REF=A; ALT=G |
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rs4986790 |
SNP |
PedAM |
snpId=rs4986790; pubmedId=20306049; geneId=7099; geneSymbol=TLR4; diseaseId=umls:C0003873; sourceId=BeFree; sentence=Lack of association of TLR4 gene Asp299Gly and Thr399Ile polymorphisms with rheumatoid arthritis in Chinese Han population of Yunnan Province.; score=0.027141644; Year=2010; geneSymbol_dbSNP=TLR4; CHROMOSOME=9; POS=117713024; REF=A; ALT=G |
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