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rs660895 |
SNP |
PedAM |
snpId=rs660895; pubmedId=23678157; geneId=640; geneSymbol=BLK; diseaseId=umls:C0003873; sourceId=BeFree; sentence=Among these associations, we found that 8 single-nucleotide polymorphisms (SNP; rs1600249, rs2736340, rs3093023, rs3093024, rs4810485, rs615672, rs660895, and rs9272219) serve as cis-effect regulators of the corresponding eQTL genes (BLK and CD4 in non-HLA region; CCR6, HLA-DQA1, and HLA-DQB1 in HLA region) that also were differentially expressed in RA-related cell groups.; score=0.128458305; Year=2014; geneSymbol_dbSNP=NA; CHROMOSOME=6; POS=32609603; REF=A; ALT=G |
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rs660895 |
SNP |
PedAM |
snpId=rs660895; pubmedId=23678157; geneId=3119; geneSymbol=HLA-DQB1; diseaseId=umls:C0003873; sourceId=BeFree; sentence=Among these associations, we found that 8 single-nucleotide polymorphisms (SNP; rs1600249, rs2736340, rs3093023, rs3093024, rs4810485, rs615672, rs660895, and rs9272219) serve as cis-effect regulators of the corresponding eQTL genes (BLK and CD4 in non-HLA region; CCR6, HLA-DQA1, and HLA-DQB1 in HLA region) that also were differentially expressed in RA-related cell groups.; score=0.051226702; Year=2014; geneSymbol_dbSNP=NA; CHROMOSOME=6; POS=32609603; REF=A; ALT=G |
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rs662 |
SNP |
PedAM |
snpId=rs662; pubmedId=25179377; geneId=5444; geneSymbol=PON1; diseaseId=umls:C0003873; sourceId=BeFree; sentence=We found that PON-1-Q192R was associated with severity of RA [remission-to-low and moderate-to-high in dominant Q/Q+Q/R vs. R/R: OR=2.27, p<0.001; codominant Q/Q vs. R/R: OR=1.65, p<0.001 and Q/R vs. R/R: OR=2.12, p=0.003; recessive Q/Q vs. R/R+Q/R: OR=1.79, p=0.032; and allele Q vs. R: OR=1.68, p<0.001] and presence of anti-CCP-antibody (codominant model Q/Q vs. R/R: OR=1.28, p=0.042).; score=0.131454097; Year=2014; geneSymbol_dbSNP=PON1; CHROMOSOME=7; POS=95308134; REF=T; ALT=C |
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rs662 |
SNP |
PedAM |
snpId=rs662; pubmedId=20198589; geneId=5444; geneSymbol=PON1; diseaseId=umls:C0003873; sourceId=BeFree; sentence=Lack of association between paraoxonase-1 Q192R polymorphism and rheumatoid arthritis in southeast Iran.; score=0.131454097; Year=2010; geneSymbol_dbSNP=PON1; CHROMOSOME=7; POS=95308134; REF=T; ALT=C |
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rs662 |
SNP |
PedAM |
snpId=rs662; pubmedId=25179377; geneId=590; geneSymbol=BCHE; diseaseId=umls:C0003873; sourceId=BeFree; sentence=Association between butyrylcholinesterase activity and phenotypes, paraoxonase192 rs662 gene polymorphism and their enzymatic activity with severity of rheumatoid arthritis: correlation with systemic inflammatory markers and oxidative stress, preliminary report.; score=0.000271442; Year=2014; geneSymbol_dbSNP=PON1; CHROMOSOME=7; POS=95308134; REF=T; ALT=C |
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rs6679677 |
SNP |
PedAM |
snpId=rs6679677; pubmedId=17554300; geneId=10745; geneSymbol=PHTF1; diseaseId=umls:C0003873; sourceId=GWASCAT; sentence=Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.; score=0.12; Year=2007; geneSymbol_dbSNP=PHTF1; CHROMOSOME=1; POS=113761186; REF=C; ALT=A |
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rs6679677 |
SNP |
PedAM |
snpId=rs6679677; pubmedId=18794853; geneId=10745; geneSymbol=PHTF1; diseaseId=umls:C0003873; sourceId=GWASCAT; sentence=Common variants at CD40 and other loci confer risk of rheumatoid arthritis.; score=0.12; Year=2008; geneSymbol_dbSNP=PHTF1; CHROMOSOME=1; POS=113761186; REF=C; ALT=A |
details
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rs6682654 |
SNP |
PedAM |
snpId=rs6682654; pubmedId=19435719; geneId=1021; geneSymbol=CDK6; diseaseId=umls:C0003873; sourceId=BeFree; sentence=However, there was no evidence for association of rs42041 (CDK6) and rs6682654 (CD244) with RA susceptibility in this UK population.; score=0.255287959; Year=2010; geneSymbol_dbSNP=CD244; CHROMOSOME=1; POS=160839213; REF=G; ALT=A |
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rs6682654 |
SNP |
PedAM |
snpId=rs6682654; pubmedId=19435719; geneId=51744; geneSymbol=CD244; diseaseId=umls:C0003873; sourceId=BeFree; sentence=However, there was no evidence for association of rs42041 (CDK6) and rs6682654 (CD244) with RA susceptibility in this UK population.; score=0.248544182; Year=2010; geneSymbol_dbSNP=CD244; CHROMOSOME=1; POS=160839213; REF=G; ALT=A |
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rs6715284 |
SNP |
PedAM |
snpId=rs6715284; pubmedId=24390342; geneId=130540; geneSymbol=ALS2CR12; diseaseId=umls:C0003873; sourceId=GWASCAT; sentence=Genetics of rheumatoid arthritis contributes to biology and drug discovery.; score=0.12; Year=2013; geneSymbol_dbSNP=ALS2CR12; CHROMOSOME=2; POS=201289674; REF=C; ALT=G |
details
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rs67250450 |
SNP |
PedAM |
snpId=rs67250450; pubmedId=24390342; geneId=221895; geneSymbol=JAZF1; diseaseId=umls:C0003873; sourceId=GWASCAT; sentence=Genetics of rheumatoid arthritis contributes to biology and drug discovery.; score=0.12; Year=2013; geneSymbol_dbSNP=JAZF1; CHROMOSOME=7; POS=28135367; REF=T; ALT=C |
details
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rs6732565 |
SNP |
PedAM |
snpId=rs6732565; pubmedId=24390342; geneId=55289; geneSymbol=ACOXL; diseaseId=umls:C0003873; sourceId=GWASCAT; sentence=Genetics of rheumatoid arthritis contributes to biology and drug discovery.; score=0.12; Year=2013; geneSymbol_dbSNP=ACOXL; CHROMOSOME=2; POS=110850255; REF=A; ALT=G |
details
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rs6822844 |
SNP |
PedAM |
snpId=rs6822844; pubmedId=20553587; geneId=59067; geneSymbol=IL21; diseaseId=umls:C0003873; sourceId=BeFree; sentence=Only one independent genetic association with rheumatoid arthritis within the KIAA1109-TENR-IL2-IL21 locus in Caucasian sample sets: confirmation of association of rs6822844 with rheumatoid arthritis at a genome-wide level of significance.; score=0.023007884; Year=2010; geneSymbol_dbSNP=NA; CHROMOSOME=4; POS=122588266; REF=G; ALT=T |
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rs6822844 |
SNP |
PedAM |
snpId=rs6822844; pubmedId=20112382; geneId=59067; geneSymbol=IL21; diseaseId=umls:C0003873; sourceId=GAD; sentence=[Our results indicate that there is an association between rs6822844 and multiple autoimmune diseases in non-European populations. Meta-analysis results strongly reinforce this robust association across multiple autoimmune diseases in both European-derived]; score=0.023007884; Year=2010; geneSymbol_dbSNP=NA; CHROMOSOME=4; POS=122588266; REF=G; ALT=T |
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rs6822844 |
SNP |
PedAM |
snpId=rs6822844; pubmedId=20553587; geneId=3558; geneSymbol=IL2; diseaseId=umls:C0003873; sourceId=GAD; sentence=[Only one independent genetic association with rheumatoid arthritis within the KIAA1109-TENR-IL2-IL21 locus in Caucasian sample sets: confirmation of association of rs6822844 with rheumatoid arthritis at a genome-wide level of significance.]; score=0.031889521; Year=2010; geneSymbol_dbSNP=NA; CHROMOSOME=4; POS=122588266; REF=G; ALT=T |
details
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rs6822844 |
SNP |
PedAM |
snpId=rs6822844; pubmedId=20553587; geneId=84162; geneSymbol=KIAA1109; diseaseId=umls:C0003873; sourceId=BeFree; sentence=Only one independent genetic association with rheumatoid arthritis within the KIAA1109-TENR-IL2-IL21 locus in Caucasian sample sets: confirmation of association of rs6822844 with rheumatoid arthritis at a genome-wide level of significance.; score=0.130011012; Year=2010; geneSymbol_dbSNP=NA; CHROMOSOME=4; POS=122588266; REF=G; ALT=T |
details
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rs6822844 |
SNP |
PedAM |
snpId=rs6822844; pubmedId=20553587; geneId=59067; geneSymbol=IL21; diseaseId=umls:C0003873; sourceId=GAD; sentence=[Only one independent genetic association with rheumatoid arthritis within the KIAA1109-TENR-IL2-IL21 locus in Caucasian sample sets: confirmation of association of rs6822844 with rheumatoid arthritis at a genome-wide level of significance.]; score=0.023007884; Year=2010; geneSymbol_dbSNP=NA; CHROMOSOME=4; POS=122588266; REF=G; ALT=T |
details
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rs6822844 |
SNP |
PedAM |
snpId=rs6822844; pubmedId=20553587; geneId=84162; geneSymbol=KIAA1109; diseaseId=umls:C0003873; sourceId=GAD; sentence=[Only one independent genetic association with rheumatoid arthritis within the KIAA1109-TENR-IL2-IL21 locus in Caucasian sample sets: confirmation of association of rs6822844 with rheumatoid arthritis at a genome-wide level of significance.]; score=0.130011012; Year=2010; geneSymbol_dbSNP=NA; CHROMOSOME=4; POS=122588266; REF=G; ALT=T |
details
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rs6822844 |
SNP |
PedAM |
snpId=rs6822844; pubmedId=20112382; geneId=3558; geneSymbol=IL2; diseaseId=umls:C0003873; sourceId=GAD; sentence=[Our results indicate that there is an association between rs6822844 and multiple autoimmune diseases in non-European populations. Meta-analysis results strongly reinforce this robust association across multiple autoimmune diseases in both European-derived]; score=0.031889521; Year=2010; geneSymbol_dbSNP=NA; CHROMOSOME=4; POS=122588266; REF=G; ALT=T |
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rs6859219 |
SNP |
PedAM |
snpId=rs6859219; pubmedId=20453842; geneId=79722; geneSymbol=ANKRD55; diseaseId=umls:C0003873; sourceId=GAD; sentence=[Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci.]; score=0.245005506; Year=2010; geneSymbol_dbSNP=ANKRD55; CHROMOSOME=5; POS=56142753; REF=C; ALT=A |
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