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rs7574865 |
SNP |
PedAM |
snpId=rs7574865; pubmedId=23450725; geneId=7128; geneSymbol=TNFAIP3; diseaseId=umls:C0003873; sourceId=BeFree; sentence=Childhood-onset RA was associated with TNFAIP3 rs10499194 (OR 0.60 [95% confidence interval 0.44-0.83]), PTPN22 rs2476601 (OR 1.61 [95% confidence interval 1.11-2.31]), and STAT4 rs7574865 (OR 1.41 [95% confidence interval 1.06-1.87]) variants.; score=0.167568474; Year=2013; geneSymbol_dbSNP=STAT4; CHROMOSOME=2; POS=191099907; REF=T; ALT=G |
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rs7574865 |
SNP |
PedAM |
snpId=rs7574865; pubmedId=20498205; geneId=3899; geneSymbol=AFF3; diseaseId=umls:C0003873; sourceId=BeFree; sentence=Eight markers (ie, rs1160542 (AFF3), rs1678542 (KIF5A), rs2476601 (PTPN22), rs3087243 (CTLA4), rs4810485 (CD40), rs5029937 (6q23), rs10760130 (TRAF1/C5) and rs7574865 (STAT4)) were significantly associated with RA by meta-analysis.; score=0.129001189; Year=2010; geneSymbol_dbSNP=STAT4; CHROMOSOME=2; POS=191099907; REF=T; ALT=G |
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rs7574865 |
SNP |
PedAM |
snpId=rs7574865; pubmedId=20498205; geneId=3798; geneSymbol=KIF5A; diseaseId=umls:C0003873; sourceId=BeFree; sentence=Eight markers (ie, rs1160542 (AFF3), rs1678542 (KIF5A), rs2476601 (PTPN22), rs3087243 (CTLA4), rs4810485 (CD40), rs5029937 (6q23), rs10760130 (TRAF1/C5) and rs7574865 (STAT4)) were significantly associated with RA by meta-analysis.; score=0.254473634; Year=2010; geneSymbol_dbSNP=STAT4; CHROMOSOME=2; POS=191099907; REF=T; ALT=G |
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rs7574865 |
SNP |
PedAM |
snpId=rs7574865; pubmedId=20498205; geneId=1493; geneSymbol=CTLA4; diseaseId=umls:C0003873; sourceId=BeFree; sentence=Eight markers (ie, rs1160542 (AFF3), rs1678542 (KIF5A), rs2476601 (PTPN22), rs3087243 (CTLA4), rs4810485 (CD40), rs5029937 (6q23), rs10760130 (TRAF1/C5) and rs7574865 (STAT4)) were significantly associated with RA by meta-analysis.; score=0.345272224; Year=2010; geneSymbol_dbSNP=STAT4; CHROMOSOME=2; POS=191099907; REF=T; ALT=G |
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rs7574865 |
SNP |
PedAM |
snpId=rs7574865; pubmedId=22937072; geneId=6775; geneSymbol=STAT4; diseaseId=umls:C0003873; sourceId=BeFree; sentence=The number of copies of the HLA-DRB1 shared epitope, and the minor alleles of the STAT4 rs7574865 and the PTPN22 rs2476601 polymorphisms have all been linked with an increased risk of developing rheumatoid arthritis.; score=0.316739695; Year=2012; geneSymbol_dbSNP=STAT4; CHROMOSOME=2; POS=191099907; REF=T; ALT=G |
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rs7574865 |
SNP |
PedAM |
snpId=rs7574865; pubmedId=19479340; geneId=3123; geneSymbol=HLA-DRB1; diseaseId=umls:C0003873; sourceId=BeFree; sentence=In addition to specific alleles of HLA-DRB1, the minor T allele of STAT4 rs7574865 SNP is a common RA risk factor in populations of European origin and Asian.; score=0.36; Year=2010; geneSymbol_dbSNP=STAT4; CHROMOSOME=2; POS=191099907; REF=T; ALT=G |
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rs7574865 |
SNP |
PedAM |
snpId=rs7574865; pubmedId=18759272; geneId=6775; geneSymbol=STAT4; diseaseId=umls:C0003873; sourceId=BeFree; sentence=The association of STAT4 polymorphism rs7574865 with RA was validated in patients of Spanish origin (for T versus G, P = 1.2 x 10(-6), odds ratio [OR] 1.59, 95% confidence interval [95% CI] 1.31-1.92), and the association was described for the first time in both clinical forms of inflammatory bowel disease, Crohn's disease and ulcerative colitis (for T versus G, P = 0.006, OR 1.29, 95% CI 1.07-1.55), and in type 1 diabetes mellitus (for T versus G, P = 0.008, OR 1.36, 95% CI 1.07-1.71).; score=0.316739695; Year=2008; geneSymbol_dbSNP=STAT4; CHROMOSOME=2; POS=191099907; REF=T; ALT=G |
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rs7574865 |
SNP |
PedAM |
snpId=rs7574865; pubmedId=23450725; geneId=6775; geneSymbol=STAT4; diseaseId=umls:C0003873; sourceId=BeFree; sentence=Childhood-onset RA was associated with TNFAIP3 rs10499194 (OR 0.60 [95% confidence interval 0.44-0.83]), PTPN22 rs2476601 (OR 1.61 [95% confidence interval 1.11-2.31]), and STAT4 rs7574865 (OR 1.41 [95% confidence interval 1.06-1.87]) variants.; score=0.316739695; Year=2013; geneSymbol_dbSNP=STAT4; CHROMOSOME=2; POS=191099907; REF=T; ALT=G |
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rs7574865 |
SNP |
PedAM |
snpId=rs7574865; pubmedId=22937072; geneId=3123; geneSymbol=HLA-DRB1; diseaseId=umls:C0003873; sourceId=BeFree; sentence=The number of copies of the HLA-DRB1 shared epitope, and the minor alleles of the STAT4 rs7574865 and the PTPN22 rs2476601 polymorphisms have all been linked with an increased risk of developing rheumatoid arthritis.; score=0.36; Year=2012; geneSymbol_dbSNP=STAT4; CHROMOSOME=2; POS=191099907; REF=T; ALT=G |
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rs7574865 |
SNP |
PedAM |
snpId=rs7574865; pubmedId=18273036; geneId=6775; geneSymbol=STAT4; diseaseId=umls:C0003873; sourceId=BeFree; sentence=To test the hypothesis that the variant haplotype of STAT4 seen in RA and SLE is also associated with pSS, we genotyped rs7574865, the most strongly disease-associated SNP in the variant STAT4 haplotype, in 124 Caucasian pSS subjects and compared them to 1143 Caucasian controls.; score=0.316739695; Year=2008; geneSymbol_dbSNP=STAT4; CHROMOSOME=2; POS=191099907; REF=T; ALT=G |
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rs7574865 |
SNP |
PedAM |
snpId=rs7574865; pubmedId=20498205; geneId=958; geneSymbol=CD40; diseaseId=umls:C0003873; sourceId=BeFree; sentence=Eight markers (ie, rs1160542 (AFF3), rs1678542 (KIF5A), rs2476601 (PTPN22), rs3087243 (CTLA4), rs4810485 (CD40), rs5029937 (6q23), rs10760130 (TRAF1/C5) and rs7574865 (STAT4)) were significantly associated with RA by meta-analysis.; score=0.277186332; Year=2010; geneSymbol_dbSNP=STAT4; CHROMOSOME=2; POS=191099907; REF=T; ALT=G |
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rs7574865 |
SNP |
PedAM |
snpId=rs7574865; pubmedId=22753649; geneId=6775; geneSymbol=STAT4; diseaseId=umls:C0003873; sourceId=BeFree; sentence=In addition, rs7574865 and rs10181656, in STAT4, were associated with ACPA-positive RA in the Swedish study.; score=0.316739695; Year=2012; geneSymbol_dbSNP=STAT4; CHROMOSOME=2; POS=191099907; REF=T; ALT=G |
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rs7574865 |
SNP |
PedAM |
snpId=rs7574865; pubmedId=20453842; geneId=6775; geneSymbol=STAT4; diseaseId=umls:C0003873; sourceId=GWASCAT; sentence=Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci.; score=0.316739695; Year=2010; geneSymbol_dbSNP=STAT4; CHROMOSOME=2; POS=191099907; REF=T; ALT=G |
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rs7574865 |
SNP |
PedAM |
snpId=rs7574865; pubmedId=25179669; geneId=6775; geneSymbol=STAT4; diseaseId=umls:C0003873; sourceId=BeFree; sentence=An updated meta-analysis of the signal transducer and activator of transcription 4 (STAT4) rs7574865 G/T polymorphism and rheumatoid arthritis risk in an Asian population.; score=0.316739695; Year=2015; geneSymbol_dbSNP=STAT4; CHROMOSOME=2; POS=191099907; REF=T; ALT=G |
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rs7574865 |
SNP |
PedAM |
snpId=rs7574865; pubmedId=19588142; geneId=6775; geneSymbol=STAT4; diseaseId=umls:C0003873; sourceId=BeFree; sentence=Association between the rs7574865 polymorphism of STAT4 and rheumatoid arthritis: a meta-analysis.; score=0.316739695; Year=2010; geneSymbol_dbSNP=STAT4; CHROMOSOME=2; POS=191099907; REF=T; ALT=G |
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rs7574865 |
SNP |
PedAM |
snpId=rs7574865; pubmedId=20498205; geneId=7185; geneSymbol=TRAF1; diseaseId=umls:C0003873; sourceId=BeFree; sentence=Eight markers (ie, rs1160542 (AFF3), rs1678542 (KIF5A), rs2476601 (PTPN22), rs3087243 (CTLA4), rs4810485 (CD40), rs5029937 (6q23), rs10760130 (TRAF1/C5) and rs7574865 (STAT4)) were significantly associated with RA by meta-analysis.; score=0.311201237; Year=2010; geneSymbol_dbSNP=STAT4; CHROMOSOME=2; POS=191099907; REF=T; ALT=G |
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rs7574865 |
SNP |
PedAM |
snpId=rs7574865; pubmedId=19588142; geneId=6775; geneSymbol=STAT4; diseaseId=umls:C0003873; sourceId=GAD; sentence=[Association between the rs7574865 polymorphism of STAT4 and rheumatoid arthritis: a meta-analysis.]; score=0.316739695; Year=2010; geneSymbol_dbSNP=STAT4; CHROMOSOME=2; POS=191099907; REF=T; ALT=G |
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rs7574865 |
SNP |
PedAM |
snpId=rs7574865; pubmedId=20498205; geneId=6775; geneSymbol=STAT4; diseaseId=umls:C0003873; sourceId=BeFree; sentence=Eight markers (ie, rs1160542 (AFF3), rs1678542 (KIF5A), rs2476601 (PTPN22), rs3087243 (CTLA4), rs4810485 (CD40), rs5029937 (6q23), rs10760130 (TRAF1/C5) and rs7574865 (STAT4)) were significantly associated with RA by meta-analysis.; score=0.316739695; Year=2010; geneSymbol_dbSNP=STAT4; CHROMOSOME=2; POS=191099907; REF=T; ALT=G |
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rs7574865 |
SNP |
PedAM |
snpId=rs7574865; pubmedId=22937072; geneId=26191; geneSymbol=PTPN22; diseaseId=umls:C0003873; sourceId=BeFree; sentence=The number of copies of the HLA-DRB1 shared epitope, and the minor alleles of the STAT4 rs7574865 and the PTPN22 rs2476601 polymorphisms have all been linked with an increased risk of developing rheumatoid arthritis.; score=0.524345611; Year=2012; geneSymbol_dbSNP=STAT4; CHROMOSOME=2; POS=191099907; REF=T; ALT=G |
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rs7574865 |
SNP |
PedAM |
snpId=rs7574865; pubmedId=23295549; geneId=1421; geneSymbol=CRYGD; diseaseId=umls:C0003873; sourceId=BeFree; sentence=Genetic polymorphism rs7574865 in STAT4 gene might be associated with RA susceptibility in total subjects, major ethnic groups and different status of anti-CCP or RF.; score=0.021986792; Year=2013; geneSymbol_dbSNP=STAT4; CHROMOSOME=2; POS=191099907; REF=T; ALT=G |
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