RABC

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Biomarkers name	Biomarker Type	Source database	Information	Details
CCL20	gene	CTD	Gene Symbol=CCL20; Gene ID=6364; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Antirheumatic Agents\|Arsenic Trioxide\|Azathioprine\|Cyclosporine\|deoxynivalenol\|Dexamethasone\|Dinoprostone\|Glucocorticoids\|Gold Sodium Thiomalate\|Leflunomide\|Methotrexate\|Methylprednisolone\|Naproxen\|Oxygen\|Ozone\|Piroxicam\|Prednisolone\|Resveratrol\|Tacrolimus\|Tobacco Smoke Pollution\|Tretinoin\|Vorinostat; Inference Score=62.32; Reference Count=192	details
HPGD	gene	CTD	Gene Symbol=HPGD; Gene ID=3248; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Arsenic Trioxide\|Betamethasone\|Cyclosporine\|Dexamethasone\|Diclofenac\|Dinoprostone\|entinostat\|Fenoprofen\|Flurbiprofen\|Indomethacin\|Ketoprofen\|Mefenamic Acid\|Meloxicam\|Methotrexate\|Oxygen\|Ozone\|Prednisolone\|Resveratrol\|tamibarotene\|Tobacco Smoke Pollution\|Tretinoin; Inference Score=61.26; Reference Count=173	details
HSPA1A	gene	CTD	Gene Symbol=HSPA1A; Gene ID=3303; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Antirheumatic Agents\|Arsenic Trioxide\|Aspirin\|Curcumin\|Cyclophosphamide\|Cyclosporine\|Dexamethasone\|Diclofenac\|Edaravone\|Famotidine\|glyphosate\|Gold\|Indomethacin\|Leflunomide\|ochratoxin A\|Oxygen\|Ozone\|Penicillamine\|Piroxicam\|Reactive Oxygen Species\|Resveratrol\|Sulfasalazine\|Tobacco Smoke Pollution\|Tretinoin\|triptolide; Inference Score=60.82; Reference Count=280	details
NR3C1	gene	CTD	Gene Symbol=NR3C1; Gene ID=2908; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Antirheumatic Agents\|Arsenic Trioxide\|Betamethasone\|Curcumin\|Cyclosporine\|Dexamethasone\|Diclofenac\|entinostat\|Glucocorticoids\|Hydrocortisone\|Leflunomide\|Methotrexate\|Oxygen\|Ozone\|Pesticides\|Phenylbutazone\|Plant Extracts\|Prednisolone\|Prednisone\|Reactive Oxygen Species\|Resveratrol\|Sulfasalazine\|Tacrolimus\|Tobacco Smoke Pollution\|Tretinoin\|triptolide\|valdecoxib\|Vorinostat; Inference Score=60.48; Reference Count=192	details
APP	gene	CTD	Gene Symbol=APP; Gene ID=351; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Arsenic Trioxide\|Chloroquine\|chloroquine diphosphate\|Curcumin\|Cyclosporine\|Dexamethasone\|Dinoprostone\|Edaravone\|Flurbiprofen\|glyphosate\|GW 506033X\|Indomethacin\|Meloxicam\|Methotrexate\|Minocycline\|Nitrites\|ochratoxin A\|Oxygen\|Ozone\|Penicillamine\|Plant Extracts\|Reactive Oxygen Species\|Resveratrol\|Salicylates\|Sulindac\|thymoquinone\|Tobacco Smoke Pollution\|Tretinoin\|valdecoxib; Inference Score=60.18; Reference Count=362	details
IL12B	gene	CTD	Gene Symbol=IL12B; Gene ID=3593; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Arsenic Trioxide\|Aspirin\|Azathioprine\|Chloroquine\|Curcumin\|Cyclophosphamide\|Cyclosporine\|deoxynivalenol\|Dexamethasone\|Dinoprostone\|Famotidine\|Freund's Adjuvant\|Hydroxychloroquine\|Indomethacin\|ochratoxin A\|Oxygen\|Ozone\|Plant Extracts\|Prednisolone\|Prednisone\|Resveratrol\|Sulfasalazine\|Thalidomide\|Tobacco Smoke Pollution\|Tretinoin\|triptolide; Inference Score=59.75; Reference Count=138	details
CCND1	gene	CTD	Gene Symbol=CCND1; Gene ID=595; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Arsenic Trioxide\|Aspirin\|Curcumin\|Cyclosporine\|deoxynivalenol\|Dexamethasone\|Diclofenac\|Dinoprostone\|entinostat\|glyphosate\|Gold\|Indomethacin\|Leflunomide\|mancozeb\|Maneb\|Methotrexate\|Naproxen\|ochratoxin A\|Oxygen\|Ozone\|Phenylbutazone\|Piroxicam\|Plant Extracts\|Quinacrine\|Reactive Oxygen Species\|Resveratrol\|Sulfasalazine\|Sulindac\|tamibarotene\|Thalidomide\|thymoquinone\|Tobacco Smoke Pollution\|tofacitinib\|Tretinoin\|triptolide\|Vorinostat; Inference Score=59.22; Reference Count=235	details
IL12A	gene	CTD	Gene Symbol=IL12A; Gene ID=3592; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Air Pollutants\|Aspirin\|Azathioprine\|Curcumin\|Cyclophosphamide\|Cyclosporine\|deoxynivalenol\|Dexamethasone\|Dinoprostone\|Famotidine\|Freund's Adjuvant\|Gold Compounds\|Indomethacin\|Methotrexate\|ochratoxin A\|Oxygen\|Ozone\|Plant Extracts\|Prednisone\|Resveratrol\|Sulfasalazine\|Thalidomide\|Tretinoin\|triptolide; Inference Score=59.18; Reference Count=204	details
CXCL1	gene	CTD	Gene Symbol=CXCL1; Gene ID=2919; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Antirheumatic Agents\|Aspirin\|Curcumin\|Cyclophosphamide\|Cyclosporine\|deoxynivalenol\|Dexamethasone\|Diclofenac\|Edaravone\|Famotidine\|Freund's Adjuvant\|Gold\|Gold Sodium Thiomalate\|Hydroxychloroquine\|Indomethacin\|Methotrexate\|Methylprednisolone\|Oxygen\|Ozone\|Piroxicam\|Prednisolone\|Resveratrol\|Sulfasalazine\|Tobacco Smoke Pollution\|Tretinoin\|triptolide\|valdecoxib; Inference Score=59.02; Reference Count=243	details
CD44	gene	CTD	Gene Symbol=CD44; Gene ID=960; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Antirheumatic Agents\|Arsenic Trioxide\|Aspirin\|Curcumin\|Cyclosporine\|Diclofenac\|entinostat\|glyphosate\|Indomethacin\|ochratoxin A\|Oxygen\|Ozone\|Piroxicam\|Plant Extracts\|Reactive Oxygen Species\|Resveratrol\|Tacrolimus\|tamibarotene\|thymoquinone\|Tobacco Smoke Pollution\|Tretinoin\|triptolide\|Vorinostat; Inference Score=58.97; Reference Count=73	details
BIRC3	gene	CTD	Gene Symbol=BIRC3; Gene ID=330; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Antirheumatic Agents\|Arsenic Trioxide\|Curcumin\|Cyclophosphamide\|Cyclosporine\|Dexamethasone\|Dinoprostone\|entinostat\|Gold\|Gold Compounds\|Indomethacin\|Leflunomide\|Methotrexate\|ochratoxin A\|Oxygen\|Plant Extracts\|Reactive Oxygen Species\|Resveratrol\|Sulindac\|Tacrolimus\|Tobacco Smoke Pollution\|Tretinoin\|triptolide\|Vorinostat; Inference Score=58.71; Reference Count=185	details
CDKN1B	gene	CTD	Gene Symbol=CDKN1B; Gene ID=1027; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Arsenic Trioxide\|Aspartame\|Aspirin\|Curcumin\|Cyclophosphamide\|Cyclosporine\|Dexamethasone\|Diclofenac\|entinostat\|Glucocorticoids\|glyphosate\|Gold\|Indomethacin\|Methotrexate\|Minocycline\|ochratoxin A\|Oxygen\|Piroxicam\|Plant Extracts\|Prednisone\|Resveratrol\|Sulindac\|Tacrolimus\|Tobacco Smoke Pollution\|Tretinoin\|triptolide\|Vorinostat; Inference Score=58.59; Reference Count=205	details
CCL3	gene	CTD	Gene Symbol=CCL3; Gene ID=6348; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Adjuvants, Immunologic\|Arsenic Trioxide\|Aspirin\|Betamethasone\|Curcumin\|Cyclophosphamide\|deoxynivalenol\|Dexamethasone\|Diclofenac\|Dinoprostone\|Edaravone\|Hydrocortisone\|Indomethacin\|Methotrexate\|Minocycline\|Naproxen\|Oxygen\|Ozone\|Penicillamine\|Pesticides\|Plant Extracts\|Prednisolone\|Resveratrol\|Thalidomide\|Tobacco Smoke Pollution\|Tretinoin; Inference Score=58.58; Reference Count=359	details
OGG1	gene	CTD	Gene Symbol=OGG1; Gene ID=4968; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Antirheumatic Agents\|Arsenic Trioxide\|Curcumin\|Cyclophosphamide\|deoxynivalenol\|Dexamethasone\|entinostat\|glyphosate\|Gold\|Indomethacin\|mancozeb\|ochratoxin A\|Oxygen\|Ozone\|Pesticides\|Reactive Oxygen Species\|Resveratrol\|tamibarotene\|Tobacco Smoke Pollution\|Tretinoin\|Vorinostat; Inference Score=58.55; Reference Count=62	details
BCL2L1	gene	CTD	Gene Symbol=BCL2L1; Gene ID=598; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Antirheumatic Agents\|Arsenic Trioxide\|Aspirin\|Azathioprine\|Chloroquine\|Curcumin\|Cyclophosphamide\|Cyclosporine\|deoxynivalenol\|Dexamethasone\|Diclofenac\|Dinoprostone\|entinostat\|glyphosate\|Gold\|Indomethacin\|Maneb\|Methotrexate\|ochratoxin A\|Oxygen\|Ozone\|Plant Extracts\|Reactive Oxygen Species\|Resveratrol\|Sulindac\|Tacrolimus\|Thalidomide\|thymoquinone\|Tobacco Smoke Pollution\|Tretinoin\|triptolide\|Vorinostat; Inference Score=58.13; Reference Count=228	details
CD14	gene	CTD	Gene Symbol=CD14; Gene ID=929; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Antirheumatic Agents\|Arsenic Trioxide\|Azathioprine\|Curcumin\|Cyclophosphamide\|Cyclosporine\|deoxynivalenol\|Dexamethasone\|Diclofenac\|glyphosate\|Hydrocortisone\|Hydroxychloroquine\|Methotrexate\|Oxygen\|Ozone\|Penicillamine\|Plant Extracts\|Resveratrol\|Sulfasalazine\|thymoquinone\|Tobacco Smoke Pollution\|Tretinoin; Inference Score=58.13; Reference Count=353	details
CTNNB1	gene	CTD	Gene Symbol=CTNNB1; Gene ID=1499; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Arsenic Trioxide\|Aspirin\|Chloroquine\|Curcumin\|Cyclosporine\|deoxynivalenol\|Dexamethasone\|Diclofenac\|Dinoprostone\|Famotidine\|glyphosate\|Hydrocortisone\|Indomethacin\|Methotrexate\|Naproxen\|ochratoxin A\|Oxygen\|Ozone\|Plant Extracts\|Quinacrine\|Reactive Oxygen Species\|Resveratrol\|Sulfasalazine\|Sulindac\|thymoquinone\|Tobacco Smoke Pollution\|Tretinoin\|Vorinostat; Inference Score=58.12; Reference Count=219	details
BID	gene	CTD	Gene Symbol=BID; Gene ID=637; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Antirheumatic Agents\|Arsenic Trioxide\|Aspirin\|Curcumin\|Cyclosporine\|deoxynivalenol\|Diclofenac\|Freund's Adjuvant\|glyphosate\|Indomethacin\|Leflunomide\|Maneb\|Methotrexate\|Minocycline\|ochratoxin A\|Oxygen\|Ozone\|Penicillamine\|Plant Extracts\|Reactive Oxygen Species\|Resveratrol\|thymoquinone\|Tobacco Smoke Pollution\|Tretinoin\|triptolide\|Vorinostat; Inference Score=58.09; Reference Count=358	details
EGFR	gene	CTD	Gene Symbol=EGFR; Gene ID=1956; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Antirheumatic Agents\|Arsenic Trioxide\|Aspirin\|Chloroquine\|Curcumin\|Cyclophosphamide\|Cyclosporine\|Dexamethasone\|Diclofenac\|Dinoprostone\|Freund's Adjuvant\|glyphosate\|Gold\|Gold Compounds\|Indomethacin\|Leflunomide\|Methotrexate\|ochratoxin A\|Oxygen\|Ozone\|Pesticides\|Piroxicam\|Plant Extracts\|Reactive Oxygen Species\|Resveratrol\|Sulfasalazine\|Tobacco Smoke Pollution\|Tretinoin\|valdecoxib\|Vorinostat; Inference Score=58.01; Reference Count=246	details
GPX1	gene	CTD	Gene Symbol=GPX1; Gene ID=2876; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Arsenic Trioxide\|Aspirin\|Auranofin\|Curcumin\|Cyclophosphamide\|deoxynivalenol\|Dexamethasone\|Diclofenac\|Dinoprostone\|glyphosate\|Indomethacin\|mancozeb\|Maneb\|Methotrexate\|Methylprednisolone\|ochratoxin A\|Oxygen\|Pesticides\|Plant Extracts\|Reactive Oxygen Species\|Resveratrol\|tamibarotene\|Thalidomide\|thymoquinone\|Tobacco Smoke Pollution\|Tretinoin\|triptolide; Inference Score=57.94; Reference Count=191	details