RABC

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Biomarkers name	Biomarker Type	Source database	Information	Details
COL1A1	gene	CTD	Gene Symbol=COL1A1; Gene ID=1277; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Angiotensin-Converting Enzyme Inhibitors\|Arsenic Trioxide\|Aspirin\|Azathioprine\|chloroquine diphosphate\|Curcumin\|Cyclosporine\|Dexamethasone\|Dinoprostone\|Enalapril\|entinostat\|Gold\|Gold Sodium Thiomalate\|Hydrocortisone\|Indomethacin\|Methotrexate\|Methylprednisolone\|Oxygen\|Ozone\|Piroxicam\|Plant Extracts\|Prednisolone\|Resveratrol\|Sulfasalazine\|Tacrolimus\|Thalidomide\|thymoquinone\|Tobacco Smoke Pollution\|Tretinoin; Inference Score=57.84; Reference Count=245	details
EGR1	gene	CTD	Gene Symbol=EGR1; Gene ID=1958; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Antirheumatic Agents\|Arsenic Trioxide\|Aspirin\|Azathioprine\|Betamethasone\|Curcumin\|Cyclophosphamide\|Cyclosporine\|deoxynivalenol\|Dexamethasone\|Diclofenac\|Enalapril\|entinostat\|glyphosate\|Gold Compounds\|Indomethacin\|Leflunomide\|Methotrexate\|Oxygen\|Ozone\|Penicillamine\|Reactive Oxygen Species\|Resveratrol\|Sulfasalazine\|Tacrolimus\|Tobacco Smoke Pollution\|Tretinoin\|valdecoxib\|Vorinostat; Inference Score=57.79; Reference Count=387	details
MYD88	gene	CTD	Gene Symbol=MYD88; Gene ID=4615; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Adjuvants, Immunologic\|Air Pollutants\|Antirheumatic Agents\|Arsenic Trioxide\|Chloroquine\|Curcumin\|Cyclosporine\|deoxynivalenol\|Dexamethasone\|Diclofenac\|Gold Compounds\|Methotrexate\|Nitrites\|ochratoxin A\|Oxygen\|Ozone\|Plant Extracts\|Resveratrol\|tamibarotene\|Thalidomide\|Tobacco Smoke Pollution\|Tretinoin; Inference Score=57.51; Reference Count=168	details
CASP3	gene	CTD	Gene Symbol=CASP3; Gene ID=836; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Arsenic Trioxide\|Aspartame\|Aspirin\|Auranofin\|Chlorambucil\|Chloroquine\|chloroquine diphosphate\|Curcumin\|Cyclophosphamide\|Cyclosporine\|deoxynivalenol\|Dexamethasone\|Diclofenac\|Dinoprostone\|Edaravone\|Enalapril\|entinostat\|Freund's Adjuvant\|Glucocorticoids\|glyphosate\|Gold\|Gold Compounds\|GW 506033X\|Hydrocortisone\|Hydroxychloroquine\|Indomethacin\|mancozeb\|Maneb\|Meloxicam\|Methotrexate\|Methylprednisolone\|Minocycline\|Misoprostol\|ochratoxin A\|Oxygen\|Ozone\|Penicillamine\|Pesticides\|Plant Extracts\|Prednisolone\|Quinacrine\|Reactive Oxygen Species\|Resveratrol\|Sulfasalazine\|Sulindac\|Tacrolimus\|Thalidomide\|thymoquinone\|Tobacco Smoke Pollution\|Tretinoin\|triptolide\|Vorinostat; Inference Score=57.33; Reference Count=432	details
PMAIP1	gene	CTD	Gene Symbol=PMAIP1; Gene ID=5366; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Antirheumatic Agents\|Arsenic Trioxide\|Aspirin\|Curcumin\|Cyclosporine\|deoxynivalenol\|Diclofenac\|entinostat\|glyphosate\|Gold\|Indomethacin\|Leflunomide\|Maneb\|Methotrexate\|ochratoxin A\|Oxygen\|Ozone\|Penicillamine\|Resveratrol\|Tobacco Smoke Pollution\|Tretinoin\|Vorinostat; Inference Score=57.22; Reference Count=349	details
LMNB1	gene	CTD	Gene Symbol=LMNB1; Gene ID=4001; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Antirheumatic Agents\|Azathioprine\|Cyclophosphamide\|Cyclosporine\|deoxynivalenol\|entinostat\|glyphosate\|Gold\|Leflunomide\|Methotrexate\|ochratoxin A\|Oxygen\|Ozone\|Resveratrol\|tamibarotene\|Tobacco Smoke Pollution\|Tretinoin\|valdecoxib\|Vorinostat; Inference Score=57.12; Reference Count=170	details
AKT1	gene	CTD	Gene Symbol=AKT1; Gene ID=207; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Antigens\|Arsenic Trioxide\|Aspirin\|Azathioprine\|Chloroquine\|chloroquine diphosphate\|Curcumin\|Cyclophosphamide\|Cyclosporine\|deoxynivalenol\|Dexamethasone\|Diclofenac\|Dinoprostone\|Edaravone\|Enalapril\|Flurbiprofen\|glyphosate\|Gold\|Hydrocortisone\|Indomethacin\|LY 117018\|mancozeb\|Maneb\|Methotrexate\|Methylprednisolone\|ochratoxin A\|Oxygen\|Ozone\|Plant Extracts\|Resveratrol\|Sulindac\|Thalidomide\|thymoquinone\|Tobacco Smoke Pollution\|tofacitinib\|Tretinoin\|triptolide\|Vorinostat; Inference Score=57.1; Reference Count=249	details
SLC22A7	gene	CTD	Gene Symbol=SLC22A7; Gene ID=10864; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Aspirin\|Cyclosporine\|Dexamethasone\|Diclofenac\|Dinoprostone\|Enalapril\|Indomethacin\|Ketoprofen\|Mefenamic Acid\|Methotrexate\|Minocycline\|Naproxen\|ochratoxin A\|Piroxicam\|Resveratrol\|Sulfasalazine\|Sulindac\|Tobacco Smoke Pollution\|triptolide; Inference Score=57.02; Reference Count=197	details
CASP7	gene	CTD	Gene Symbol=CASP7; Gene ID=840; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Antirheumatic Agents\|Arsenic Trioxide\|Aspirin\|Chloroquine\|Curcumin\|Cyclosporine\|deoxynivalenol\|Dexamethasone\|Edaravone\|glyphosate\|Gold\|Gold Compounds\|Indomethacin\|mancozeb\|Maneb\|Methotrexate\|Minocycline\|ochratoxin A\|Ozone\|Plant Extracts\|Reactive Oxygen Species\|Resveratrol\|thymoquinone\|Tobacco Smoke Pollution\|Tretinoin\|triptolide\|Vorinostat; Inference Score=56.95; Reference Count=208	details
GPX3	gene	CTD	Gene Symbol=GPX3; Gene ID=2878; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Antirheumatic Agents\|Arsenic Trioxide\|Azathioprine\|Cyclophosphamide\|Cyclosporine\|deoxynivalenol\|Dexamethasone\|Flurbiprofen\|glyphosate\|Indomethacin\|Methotrexate\|ochratoxin A\|Oxygen\|Ozone\|Pesticides\|Plant Extracts\|Resveratrol\|Sulfasalazine\|Sulindac\|Tobacco Smoke Pollution\|Tretinoin\|triptolide; Inference Score=56.82; Reference Count=188	details
PLA2G4A	gene	CTD	Gene Symbol=PLA2G4A; Gene ID=5321; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Arsenic Trioxide\|Aspirin\|Cyclophosphamide\|Cyclosporine\|Dexamethasone\|Dinoprostone\|entinostat\|Flurbiprofen\|Freund's Adjuvant\|Methotrexate\|Methylprednisolone\|Oxygen\|Ozone\|Plant Extracts\|Prednisolone\|Resveratrol\|Sulindac\|Tobacco Smoke Pollution\|Tretinoin\|Vorinostat; Inference Score=56.74; Reference Count=174	details
IL13	gene	CTD	Gene Symbol=IL13; Gene ID=3596; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Adjuvants, Immunologic\|Air Pollutants\|Antigens\|Arsenic Trioxide\|Aspirin\|Chloroquine\|Dexamethasone\|Dinoprostone\|Freund's Adjuvant\|glyphosate\|Leflunomide\|Methotrexate\|Naproxen\|ochratoxin A\|Ozone\|Penicillamine\|Pesticides\|Plant Extracts\|Prednisolone\|Prednisone\|Resveratrol\|Tobacco Smoke Pollution\|Tretinoin; Inference Score=56.69; Reference Count=364	details
HGF	gene	CTD	Gene Symbol=HGF; Gene ID=3082; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Antirheumatic Agents\|Arsenic Trioxide\|Aspartame\|Aspirin\|Curcumin\|Cyclosporine\|Dexamethasone\|Dinoprostone\|entinostat\|Freund's Adjuvant\|glyphosate\|Hydrocortisone\|ochratoxin A\|Oxygen\|Plant Extracts\|Reactive Oxygen Species\|Resveratrol\|Sulfasalazine\|Thalidomide\|Tobacco Smoke Pollution\|Tretinoin\|Vorinostat; Inference Score=55.95; Reference Count=74	details
GADD45A	gene	CTD	Gene Symbol=GADD45A; Gene ID=1647; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Arsenic Trioxide\|Aspirin\|Curcumin\|Cyclophosphamide\|Cyclosporine\|deoxynivalenol\|Dexamethasone\|Diclofenac\|glyphosate\|Gold Compounds\|Indomethacin\|Leflunomide\|mancozeb\|Methotrexate\|ochratoxin A\|Oxygen\|Ozone\|Penicillamine\|Pesticides\|Plant Extracts\|Resveratrol\|Sulindac\|tamibarotene\|Tobacco Smoke Pollution\|Tretinoin\|Vorinostat; Inference Score=55.93; Reference Count=358	details
ATF6	gene	CTD	Gene Symbol=ATF6; Gene ID=22926; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Antirheumatic Agents\|Arsenic Trioxide\|Curcumin\|Cyclosporine\|deoxynivalenol\|Dexamethasone\|Gold\|Indomethacin\|Minocycline\|ochratoxin A\|Oxygen\|Penicillamine\|Plant Extracts\|Reactive Oxygen Species\|Resveratrol\|Tacrolimus\|thymoquinone\|Tobacco Smoke Pollution\|Tretinoin\|triptolide; Inference Score=55.88; Reference Count=226	details
CHUK	gene	CTD	Gene Symbol=CHUK; Gene ID=1147; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Arsenic Trioxide\|Aspirin\|Auranofin\|Aurothioglucose\|Chloroquine\|Curcumin\|Cyclosporine\|deoxynivalenol\|Dexamethasone\|Diclofenac\|Freund's Adjuvant\|Gold Sodium Thiomalate\|GW 506033X\|Maneb\|Phenylbutazone\|Plant Extracts\|Resveratrol\|Sulindac\|Thalidomide\|thymoquinone\|Vorinostat; Inference Score=55.88; Reference Count=93	details
IL5	gene	CTD	Gene Symbol=IL5; Gene ID=3567; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Adjuvants, Immunologic\|Air Pollutants\|Curcumin\|Cyclophosphamide\|Cyclosporine\|deoxynivalenol\|Dexamethasone\|Diclofenac\|Dinoprostone\|Freund's Adjuvant\|Glucocorticoids\|glyphosate\|Hydrocortisone\|Methylprednisolone\|Naproxen\|Ozone\|Plant Extracts\|Prednisolone\|Prednisone\|Reactive Oxygen Species\|Resveratrol\|Tacrolimus\|Thalidomide\|Tretinoin; Inference Score=55.83; Reference Count=77	details
JUN	gene	CTD	Gene Symbol=JUN; Gene ID=3725; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Antirheumatic Agents\|Arsenic Trioxide\|Aspirin\|Azathioprine\|Curcumin\|Cyclosporine\|deoxynivalenol\|Dexamethasone\|Diclofenac\|Freund's Adjuvant\|glyphosate\|Gold\|Hydroxychloroquine\|Indomethacin\|Leflunomide\|Maneb\|Methotrexate\|Minocycline\|ochratoxin A\|Oxygen\|Ozone\|Pesticides\|Plant Extracts\|Prednisone\|Reactive Oxygen Species\|Resveratrol\|Sulindac\|Tacrolimus\|Thalidomide\|Tobacco Smoke Pollution\|tofacitinib\|Tretinoin\|Vorinostat; Inference Score=55.78; Reference Count=235	details
TNFRSF10B	gene	CTD	Gene Symbol=TNFRSF10B; Gene ID=8795; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Antirheumatic Agents\|Arsenic Trioxide\|Aspirin\|Chlorambucil\|Chloroquine\|Curcumin\|Cyclosporine\|Dexamethasone\|Diclofenac\|entinostat\|glyphosate\|Indomethacin\|Methotrexate\|Oxygen\|Ozone\|Plant Extracts\|Resveratrol\|Sulindac\|Thalidomide\|thymoquinone\|Tretinoin\|triptolide\|Vorinostat; Inference Score=55.5; Reference Count=196	details
CDKN1A	gene	CTD	Gene Symbol=CDKN1A; Gene ID=1026; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Antirheumatic Agents\|Arsenic Trioxide\|Aspirin\|Auranofin\|Azathioprine\|Chlorambucil\|Chloroquine\|Curcumin\|Cyclophosphamide\|Cyclosporine\|deoxynivalenol\|Dexamethasone\|Diclofenac\|entinostat\|Glucocorticoids\|glyphosate\|Indomethacin\|Leflunomide\|mancozeb\|Maneb\|Methotrexate\|ochratoxin A\|Oxygen\|Ozone\|Piroxicam\|Plant Extracts\|Prednisone\|Resveratrol\|Sulfasalazine\|Sulindac\|tamibarotene\|thymoquinone\|Tobacco Smoke Pollution\|Tretinoin\|triptolide\|Vorinostat; Inference Score=55.48; Reference Count=254	details